A study spanning more than seven years has found no significant health risks associated with the long-term consumption of genetically modified (GM) maize in cynomolgus macaques. Conducted across two generations of the non-human primates, the research assessed the impact of GM maize on immune responses and metabolic health.

The study evaluated a GM maize line containing insect-resistant and herbicide-tolerant traits (cry1Ab/cry2Aj and G10evo–EPSPS genes). In both generations, the researchers performed detailed analyses on immunoglobulin profiles, cytokine networks, and serum metabolome characteristics. While some minor differences in blood and metabolic parameters emerged, none were deemed biologically or clinically significant. The research also ruled out concerns related to chronic inflammation, autoimmune responses, or toxicity from GM maize.

The findings provide substantial evidence to support the global body of research on the safety of GM crops. While the study did not assess cellular and mucosal immunity, it establishes a methodological framework for longitudinal safety assessments of GM crops. The researchers conclude that the prolonged consumption of GM maize poses no significant health risks.

A version of this article was originally posted at ISAAA.org and is reposted here with permission. Any reposting should credit both the GLP and original article. Find ISAAA.org on X @isaaa_org